HCS307 Assignment 1: Laboratory investigation of haematological malignanciesGuidelines for writing the assignment
\nLearning outcome: Evaluate the laboratory investigation approach in the diagnosis and monitoring
\nof a patient with chronic myeloid leukaemia.
\nAssessment will be based on the following criteria:
\nCritical analysis and interpretation of laboratory testing
\n\u2013 Evaluation of laboratory testing within haematological malignancies
\n\u2013 Evidence of understanding
\n\u2013 Clarity and validity of reasoning
\n\u2013 Support for key points with appropriate evidence
\nPresentation
\n\u2013 Structure, formatting, proper headings, spacing, consistent and correct referencing style
\nInstructions:
\nYou are asked to answer the following questions regarding the evaluation and laboratory diagnosis
\nand monitoring of a patient with chronic myeloid leukaemia.
\nThe assignment will contribute 20% to your final mark. WORD LIMIT 1500
\nDeadline: Midnight, Sunday 21st February 2016
\nQuestions (mark allocation, %):
\n1) Explain the pathogenesis of chronic myeloid leukaemia (CML) (40 %)
\n\u2022 The cellular and molecular changes you describe here should complement your
\nexplanation of the methodology used to form a diagnosis of CML
\n2) An investigative approach will start with a haematological profile before using cytogenetic
\nand molecular techniques to confirm a diagnosis and monitor treatment response. Discuss
\nthe information which can be provided from the following techniques. Include in your
\nanswer typical findings in a patient with CML, limitations of the techniques, and how these
\ntechniques are used to evaluate treatment response:
\na. Full blood count and blood film (10 %)
\nb. Cytogenetic tests (20 %)
\nc. Molecular tests (20 %)
\nMake sure that you reference your work accurately, and remember that the presentation of your
\nwork as well as the content will count towards your mark (10 %)
\nYou may use the following review article for guidance:
\nTohami T, Nagler A, Amariglio NA (2012) Laboratory tools for diagnosis and monitoring response in
\npatients with chronic myeloid leukemia. IMAJ: 14, 501-507<\/p>\n","protected":false},"excerpt":{"rendered":"
HCS307 Assignment 1: Laboratory investigation of haematological malignanciesGuidelines for writing the assignment Learning outcome: Evaluate the laboratory investigation approach in the diagnosis and monitoring of a patient with chronic myeloid leukaemia. Assessment will be based on the following criteria: Critical Read More …<\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-95544","post","type-post","status-publish","format-standard","hentry"],"_links":{"self":[{"href":"https:\/\/www.benedictsol.com\/blogs\/wp-json\/wp\/v2\/posts\/95544","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.benedictsol.com\/blogs\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.benedictsol.com\/blogs\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.benedictsol.com\/blogs\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.benedictsol.com\/blogs\/wp-json\/wp\/v2\/comments?post=95544"}],"version-history":[{"count":0,"href":"https:\/\/www.benedictsol.com\/blogs\/wp-json\/wp\/v2\/posts\/95544\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.benedictsol.com\/blogs\/wp-json\/wp\/v2\/media?parent=95544"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.benedictsol.com\/blogs\/wp-json\/wp\/v2\/categories?post=95544"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.benedictsol.com\/blogs\/wp-json\/wp\/v2\/tags?post=95544"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}